Description of courses for 6-year Pharm.D. Program

  • Biophysics

    During the course students are provided with the information on making laboratory measurements, correct presentation and interpretation of their results and estimation of the experimental uncertainties. Students also acquire the ability of proper handling of laboratory equipment.

    The selected laboratory topics concern the physical aspects of:

    • biological processes: diffusion across membranes, some aspects of creation and propagation of the action potential
    • molecular interactions: electrochemical potentials, viscosity, thin films and surface tension
    • interaction of ionizing radiation with matter
    • application and handling of chosen devices in the laboratory diagnostics: microscope, spectrophotometer, polarimeter, radiometer.
  • Biology and Botany

    This course consists of:

    • elements of organization of living matter
    • functioning of organisms
    • elements of ecology
    • elements of parasitology and evolution of the parasite-host system
    • cytophysiology — cell physiology
    • elements of classical, population, and molecular genetics
    • morphological and anatomic characteristics of major systematic units of prokaryotic organisms, fungi, and plants delivering medicinal materials used in pharmacy
    • research methods in taxonomy
    • recognition of cell and tissue components as well as of organs and species of pharmaceutical significance
    • elements of the biotechnology of superior plants — plant growth regulators, in-vivo cultures, and microreproduction
    • biotechnology in collecting medicinal materials
    • plant protection systems
    • methods of searching for new medical plants — ethnobotany
    • medicinal and protected plants in natural conditions and cultivated
    • medicinal plant herbarium
  • Biophysics

    This course covers:

    • physical fundamentals of physiological processes — circulation, nerve conduction, gas exchange, kinesis, and substance exchange
    • influence of physical factors on the environment of living organisms
    • methodology of measuring the biophysical values
    • biophysical aspects of diagnostics and therapy
  • Mathematics and Statistics

    This course focuses on:

    • elementary functions
    • inverse functions
    • elements of differential and integral calculus
    • first-order differential equations
    • elements of probability calculus and mathematical statistics — probability of the event occurrence,
    • random variables and their distribution, and an average value and its variance
    • basic distributions of random variables
    • point and interval estimation of parameters
    • testing statistical hypotheses
    • correlation and regression
  • First Aid

    • recognition of health hazards and life-threatening situations
    • evaluation of basic vital signs in emergency situations
    • recovery and stabilization of basic life functions, including the functions of the circulatory and respiratory systems
    • protection and stabilization of different areas of the human body in patients with external injuries
    • performance of life-saving procedures in specific types of environmental hazards
    • organization and management of certified and safe transportation modes for people in emergency situations
  • General and Inorganic Chemistry

    • atoms and particles
    • the periodic table of elements
    • radioactive isotopes and their applications to diagnostics and treatment
    • mechanisms of creation and types of chemical bonds
    • complex compounds
    • states of matter concentration
    • solutions
    • oxidation and reduction processes
    • characteristics of metals and non-metals
    • identification of inorganic substances
    • application of inorganic substances in pharmacy
  • Medical Anatomy

    • fundamentals of human anatomy
    • elements of functional and developmental anatomy
    • interdependence between the structure and function of the body in sickness and in health
  • History of Pharmacy

    • history of pharmaceutical agents and pharmaceutics
    • evolution of pharmaceutical knowledge
    • developments in pharmaceutical sciences
    • history of pharmacies and pharmaceutics
    • historical roots of pharmacy education
    • medical and pharmaceutical traditions and culture
  • Chemical, Instrumental, and Pharmaceutical Analysis

    • classical methods of quantitative analysis — gravimetric analysis, bulk analysis, alkalimetry and acidimetry, redoxymetry, argentometry, complexometry, and gas analysis
    • the characteristics and classification of instrumental methods
    • spectroscopic, electrochemical, and separation methods
  • Organic Chemistry

    • classification of carbon compounds — rules for nomenclature
    • structure of organic compounds within the framework of the theory of atomic and molecular orbitals
    • mesometric and inductive effects
    • types of chemical reactions — substitution, addition, and elimination
    • mechanisms of chemical reactions
    • systematics of organic compounds according to the function groups occurring in them
    • properties of: carbohydrates, fluorohydrates, organometallic compounds, amines, nitro compounds, alcohols, phenols, ethers, aldehydes, ketons, carboxylic acids, the function and skeletal derivatives of carboxylic acids, and derivatives of carbonic acid
    • the structure and properties of five- or six-membered heterocyclic compounds containing the N, O, and S atoms
    • the structure and properties of natural compounds: alkaloids, carbohydrates, steroids, terpenes, lipids, peptides, and proteins
    • preparation of compounds
    • analysis of organic compounds
  • Physical Chemistry

    • elements of quantum mechanics
    • elements of chemical thermodynamics and kinetics
    • mechanisms of catalysis
    • polyphasic system physiocochemistry and physiocochemistry of surface phenomena
    • elements of electrochemistry
    • physiocochemical fundamentals of pharmacokinetics
  • Microbiology

    • general and particular bacteriology
    • elements of virology and mycology
    • characteristics of bacteria, viruses, and pathogenic fungi
    • the influence of chemotherapeutics, disinfectants, and antiseptics on microorganisms
    • elements of microbiological diagnostics
    • fundamentals of pharmaceutical microbiology
  • Pharmacology

    • general pharmacology
    • mechanisms of drug actions
    • pharmacological effects
  • Pharmacognosy and Natural Drugs

    • acquisition of medicinal materials of natural origin — mainly of plant origin
    • biologically active compounds of plant origin, with their chemical composition and effects:
      • primary metabolites — carbohydrates, fats, and proteins
      • secondary metabolites — glycosides, terpenoids, phenylpropanoids, alkaloids
    • the pharmacopoeial and non-pharmacopoeial materials containing biologically active compounds of plant origin
    • identification, quality assessment, and standardization of medicinal plant materials
    • drugs of different origins: mineral, viral, bacterial, fungal, plant, and animal
    • natural drugs in a pharmacological arrangement — composition, form, action, application, and dosage
    • pharmaceutical preparations available in the market
    • mineral preparation, bacterial preparations (enzymes), and animal preparations (enzymes, venoms, and proteins)
    • preparations used in apitherapy
    • plant medicines and mixtures of plant materials
    • Galenic preparations — compositions
    • domestic and foreign preparations
    • the place of phytotherapy in contemporary health care
    • quality assessment of plant-derived medicines
    • rules governing introduction of plant-derived medicines to the pharmaceutical market
  • Introduction to Applied Pharmacy

    • rules related to good pharmacy practice in the context of pharmaceutical care
    • rules for dispensing of prescriptions
    • distribution of over-the-counter (OTC) drugs
    • the operation of pharmacy computer programs
    • drug information
    • counseling for independent use of drugs
    • interactions and risks in multidrug therapy
    • elements of interpersonal communication
    • elements of marketing and management
  • Physiological and Pathophysiological Bases for Therapeutics

    • elements of cytophysiology
    • mechanisms of nervous and hormonal regulation
    • elements of the physiology of major body systems: integumentary, musculo-skeletal, cardiovascular, lymphatic, respiratory, digestive, nervous, endocrine, urinary, reproductive, and body fluid(s) and electrolytes
    • secretion and thermoregulation
    • adaptive mechanisms
    • influence of drugs on physiological functions of the human body
    • elements of cell pathophysiology
    • disorders of the adaptive functions of the body
    • pathophysiology of the blood and the immune system
    • disorders of the body’s self-regulation
    • fundamentals of pathophysiology of selected body systems
    • mechanisms of neoplasm development
    • metabolic disorders
    • elements of etiology
  • Pharmaceutical Technology

    • characteristics and requirements for various forms of drug delivery
    • unit processes and adjuvant substances
    • methods of liquid, semisolid, and solid drug preparation
    • Good Manufacturing Practice (GMP) rules for drugs
    • good preparation practice rules for prescription drugs
    • quality and stability of dosage forms
    • biopharmaceutical aspects of formulating dosage forms
  • Hygiene and Epidemiology

    • environmental factors affecting human health
    • environmental pollution connected with human activity
    • hygiene of environmental elements: air, water, and soil
    • hygiene of the human dwelling and workplace environments — occupational diseases
    • environmental factors of neoplastic diseases
    • disease prevention
    • safety, occupational hygiene, and ergonomics in pharmacy
    • mental hygiene and addiction prevention
    • elements of epidemiology — planning, methodology, and strategy for epidemiological research
    • epidemiological databases
  • Biochemistry

    • protein structure and biological functions
    • enzymology
    • structure and functions of biological membranes
    • transportation mechanisms
    • molecular aspects of signal transduction
    • biological oxidation and bioenergetics
    • metabolism of carbohydrates and lipids
    • catabolism of proteins, amino acids, and biogenic amines
    • molecular mechanisms of DNA, RNA, and protein biosynthesis
    • mutagenesis and DNA repair systems
    • molecular mechanisms for the biotransformation of drugs
    • integration and regulation of metabolic processes
    • drugs as modificators of the metabolic processes
  • Biotechnology

    • productive potential of living cells and organisms — biochemical fundamentals and possibilities of regulation with technological processes
    • culture of microorganisms, and in-vitro cultures of animal and plant cells — management of the biosynthesis and biotransformation processes from the pharmaceutical production perspective
    • the obtaining and applications of immobilized biocatalysts
    • applications of the protoplast fusion
    • molecular biotechnology — obtaining and inserting genes into cells of plant and animal microorganisms, gene expression regulation, and production of pharmaceuticals with the recombinant DNA technology
    • the concept of gene therapy
    • insertion of genes and inhibition of gene expression in the organism
  • Patient Care

    • causes of medication errors/systems approaches
    • the human factor in errors
    • strategies for reducing human errors
    • pharmacy leadership in medication safety
  • Medicinal Chemistry

    A review of medicinal substances in the pharmacological arrangement with particular reference to international nomenclature and synonyms for basic preparations used in the pharmacotherapy of: diseases of the central and peripheral nervous systems, cardiovascular system, digestive system, and the excretory system; as well as in demonstrating the anti-infective activity of drugs used in hormone therapy, vitamins, and enzymes.

    Relationships between the structure of a medicinal substance and the mechanism of action with respect to the therapeutic usefulness of drugs, in the context of the biochemical mechanism of their action, routes of drug administration, drug distribution in the body, biotransformation, and their adverse and toxic effects.

    Quality control of drugs in accordance with the Polish Pharmacopoeia and the European Pharmacopoeia.

    Classical and instrumental methods in the assessment of medicinal substances and their dosage forms.

  • Drug Synthesis

    • search methods for biologically active compounds — leads and their optimization
    • high throughput screening and combinatorial chemistry
    • selected methods for obtaining intermediate and final products in the synthesis of medicinal substances
    • physical and chemical unit processes — their economics and ecology
    • optical isometry and the methods of obtaining optically active compounds as a result of the division of racemates and asymmetric synthesis
    • polymorphism
    • Good Manufacturing Practice (GMP)
    • the pharmaceutical industry in Poland
    • patent protection
    • synthesis of selected drugs
  • Immunology and Oncology

    • competent immunological cells
    • antigens and antibodies
    • the mechanisms of immune response
    • non-specific immunity — interferons and the complement system
    • regulation of immune processes
    • elements of immunopathology
    • oversensitivity and allergic diseases
    • autoimmunization
    • tumor immunology
    • elements of transplantation immunology
    • immunoprophylaxis and immunotherapy
    • elements of immunological diagnostics
  • Clinical Nutrition and Health Promotion

    • influence of nutrients on human health
    • nutritional recommendations regarding food composition and diet in the prevention of civilization-related diseases — arteriosclerosis, diabetes, obesity, osteoporosis, and food allergies
    • role of vitamins and the macro- and microelements in nutritional therapy
    • medicinal products containing dietary supplements
    • food products with special nutritional designations
    • dietary supplements
    • health and analytical aspects of: fortified foods, functional foods, novel foods
    • food additives
    • food contamination
    • drug interaction with selected food components
    • health-related quality control in food
    • analytics in food control
  • Communication, Behavior, and Ethics in Pharmacy Practice

    • pharmaceutical ethics as well as medical and dental ethics — definitions and ethical systems
    • fundamentals of bioethics
    • code of ethics for pharmacists
    • shaping of sensitivity as well as of moral and ethical attitudes as the basis for  pharmaceutical care
  • Toxicology

    • the role and challenges for contemporary toxicology
    • toxins, toxicity levels, and forms of intoxication
    • the effects of xenobiotics on the body — absorption, distribution, and biotransformation
    • Phase I and Phase II reactions
    • inhibition and induction of microsomal enzymes
    • mechanisms of toxic action and bioactivation
    • distant toxic effects
    • toximetry
    • investigation and evaluation of the acute, subacute, and chronic toxicity, as well as of the carcinogenic, mutagenic, and teratogenic activity
    • contemporary toxicological analysis — methods of detection and determination of xenobiotics in the biological material and of the environmental elements
    • toxicomanias
    • environmental toxicology
    • chemical safety and exposure assessment
  • Advanced Pharmacotherapy

    • pharmacotherapy of selected diseases with special regard for civilization-related diseases and the diseases requiring long-term treatment
    • monotherapy and polypragmasy
    • drug-induced complications
    • individualization of pharmacotherapy determined by age, pathological states, genetic, and environmental factors
    • monitoring of adverse drug effects
    • sources for data acquisition, documentation, and forms of information exchange
    • contemporary aspects of the doctor-pharmacist and the pharmacist-patient cooperation
  • Pharmacokinetics

    • the fate of drugs in the body – absorption, distribution, and elimination
    • the determination of pharmacokinetic parameters using compartment and physiological models as well as non-model-based techniques
    • single and multiple drug administration and the inert state
    • influence of pathological states as well as the genetic and environmental factors on drug pharmacokinetics
    • fundamentals of therapeutic drug monitoring